Soybean meal is a byproduct from the process of soybean oil extraction, which is mainly composed of protein (40% ~ 44%), fat (1% ~ 2%), carbohydrate (10% ~ 15%), and a variety of minerals, vitamins and essential amino acids. Its nutrition is relatively comprehensive and balanced. In addition, soybean meal also contains soy isoflavones, phospholipids and other bioactive substances, which is the most widely used plant-based protein resources. However there are many kinds of antinutritional factors in soybean meal (trypsin inhibitors, soybean protein antigen, urease, phytic acid, etc.). On one hand, their existence has inhibition effect on certain digestive enzyme when they are combined with some nutrient component and forms the production that is difficult to digest and absorb. On the other hand, some of them can cause the organ damage of animals and leave bad influence on health and growth. Fermented soybean meal, also known as the microorganism fermented soybean meal the produced under controlled condition, making use of microbial growth, reproduction and metabolism and the accumulation of useful enzyme and intermediate metabolites of bacteria. Through the microbial fermentation, the fermented soybean meal contains little antinutritional factors and is rich in small molecule soybean peptide, amino acids, enzymes, vitamin and bioactive factors, which has good palatability. It can be applied to the piglets feeding, poultry feeding, and aquaculture. It is ideal alternatives to fish meal with huge market potential and economic value.